Tom, complete with mortarboard, is teaching a kitten the basics: "cats chase mice." But Jerry keeps subverting this lesson at every opportunity.
Tom pretends to have a cold in order to trick Mammy into letting him stay inside for the night. Jerry tricks Tom by making him think he really is sick - with the measles.
The popular cartoon cat and mouse are thrown into a feature film. The story has the twosome trying to help an orphan girl who is being berated and exploited by a greedy guardian.
Someone drops off three cute little kittens; Tom is put in charge of them while Mammy goes shopping. But behind her back, the three little angels are real devils.
Tom invites Toots to an elegant dinner. However, he's made the mistake of trying to put Jerry to work, as a serving boy, a corkscrew, and other tasks. Jerry puts up with a little of this, but mostly gets revenge on Tom.
Jerry and his diapered little mouse friend flood the kitchen, then use the freezer to turn it into a skating rink. Even though Tom finds a pair of ice skates, the mice have no problem outmaneuvering him.
Jasper is given an ultimatum by his master: break one more thing and you're out. Rodent Jerry does his best to make sure that his tormentor "gets the boot".
Jerry Mouse befriends a newly hatched duckling who can't swim and ends up protecting him against his feline nemesis, Tom.
Speedy comes to the aid of a group of mice trying to get the cheese from a factory guarded by Sylvester.
Tom steals an egg from a mother duck's nest, but soon the resultant hatchling runs away from the cat and into a mouse hole, where it finds an able protector in Jerry.
The couple that owns Tom and Spike decides they can't afford to keep both. They agree that the first one to catch the mouse can stay - bad news for Jerry.
Pluto and Pluto Junior are enjoying a lazy afternoon snooze when the playful pup tangles with a ball, a balloon, a worm, a bird, and a clothesline. Pluto rescues his son from a precarious situation, gets hung up in the process, but manages to land with a splash.
Donald catches his nephews swimming on a school day. He thinks he's made an easy catch, but the boys are much more resourceful than that. When he tries to smoke them out of their clubhouse, they put three roast turkeys in their bed and dress one boy as an angel.
Tom chases Jerry into a bottle of invisible ink, and the now-invisible Jerry proceeds to have fun torturing Tom.
Mickey's trying to do some yardwork, but Pluto wants to play. They end up indoors; Mickey breaks a screen, spreads flypaper, and they both get stuck.
Tom's cousin George, who's terribly afraid of mice, comes to visit. Jerry's confused, since Tom and George look alike.
Jerry agrees to help an escaped circus lion, whose first need is food. But first they'll have to evade Tom, who heard the news bulletin and is armed with a shotgun.
Three orphan kittens are entering a society house in winter and ruin the furniture. But when they're caught by the maid, the young daughter of the house "rescues" them from the cold outside.
Even with his long white beard and aching back, an aging Donald still has to make ends meet by lancing trash in the park. When he happens upon his old partner, an elderly honey bee named Spike, it conjures up memories of the good ol' days.
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